Copley Glaxo Impactor Glass Twin Impinger 8901 in a Set of Glassware

Artikelnummer: 1863

Kategorie: Sonstiges

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821,84 £

Endpreis* , zzgl. (Paket)

COPLEY scientific

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Manufacturer: Copley Scientific Ltd.

Model: Glaxo Impactor Glass Twin Impinger 8901

MFG: 2010

S/N: 524G
P/N: 8901

Description incl. features and specifications:

The value of this glass twin impinger, particularly with respect to routine quality control, is recognised by its retention as Apparatus A in Ph.Eur. 2.9.18.
Its usage is restricted to the assessment of nebulisers, MDIs and such DPIs where it can be demonstrated that a flow rate of 60 (+/-5) L/min is suitable.
Developed at GSK’s laboratories in Ware, UK, it is relatively easy to use and assemble.
The major advantage is that it is manufactured solely from glass so that it is not prone to corrosion in the same way as conventional metallic impactors.
This glass twin impinger comes complete with stainless steel base plate, stand, clamp and boss head in addition to plastic clips to retain the glass parts in position.
The unit consists of the following glassware: Throat (Ph.Eur. Code B), Neck (Ph.Eur. Code C), Upper Impingement Chamber (Ph.Eur. Code D), Coupling Tube (Ph.Eur. Code E), Screwthread Side-Arm Adapter (Ph.Eur. Code F)
, Lower Jet Assembly (Ph.Eur. Code G), Lower Impingement Chamber (Ph.Eur. Code H), Throat Flow Meter Adapter (Ph.Eur. Code I) and Vacuum Pump Adapter (Ph.Eur. Code J).
Spare Set of Glassware also includes a set of 2 Conical Joint Clips (Yellow) and a set of 4 Conical Joint Clips (Green).

It operates on the principle of liquid impingement to divide the dose emitted from the inhaler into respirable and non-respirable fractions.
The non-respirable dose impacts on the oropharynx and is subsequently swallowed.
This is considered as the back of the glass throat and the upper impingement chamber (collectively described as Stage 1).
The remaining respirable dose penetrating the lungs is collected in the lower impingement chamber (Stage 2).
The upper impingement chamber is designed such that at a flow rate of 60 L/min through the impinger, the particle cut-off is 6.4 microns.
Particles smaller than 6.4 microns pass into the lower impingement chamber.

Prior to testing, 7 mL of solvent is typically dispensed into the upper impingement chamber and 30 mL to the lower impingement chamber.
After the test is complete, the active drug collected in the lower impingement chamber is assayed and expressed as a respirable fraction (or percentage) of the delivered dose.

Items delivered:

- Copley Glaxo Impactor Glass Twin Impinger in a Set of Glassware incl. 2 Conical Joint Clips (Yellow) and 4 Conical Joint Clips (Green)
- Stainless steel base plate, stand, clamp and boss head in addition to plastic clips to retain the glass parts in position
- Instruction manual

Condition:

The whole unit is in a perfect, like new cosmetical condition, 100% functionally tested and ready to be applied.

Versandgewicht:	10,00 kg

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